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BuSpar is an antianxiety agent that is not chemically or pharmacologically related to the barbiturates , benzodiazepines, or other sedative/anxiolytic drugs.
Buspar is a white crystalline, water soluble compound with a molecular weight of 422.0.
BuSpar is available as tablets for oral administration containing 5 mg, 10 mg, 15 mg, or 30 mg of buspirone hydrochloride. The 5 mg and 10 mg tablets are scored so they can be divided into two parts. The 5 mg tablet can also supply a 2.5 mg dose, and the 10 mg tablet can provide a 5 mg dose. The 15 mg and 30 mg tablets are supplied in the DIVIDOSE tablet design. These tablets are scored so they can be either bisected or divided into three parts. Thus, a single 15 mg tablet can provide the following divided doses: 15 mg (entire tablet), 10 mg (two thirds of a tablet), 7.5 mg (one half of a tablet), or 5 mg (one third of a tablet). A single 30 mg tablet can give the following doses: 30 mg (entire tablet), 20 mg (two thirds of a tablet), 15 mg (one half of a tablet), or 10 mg (one third of a tablet). BuSpar Tablets contain the following inactive ingredients: colloidal silicon dioxide, lactose, microcrystalline cellulose, magnesium steara and sodium starch glycolate. The 30 mg tablet also has iron oxide.
BuSpar is indicated for the management of short-term relief of the symptoms of anxiety or anxiety disorders. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic medication.
The efficacy of BuSpar has been demonstrated in controlled clinical trials of outpatients whose diagnosis roughly corresponds to GAD. Many of the patients enrolled in these studies also had coexisting depressive symptoms and this drug relieved anxiety in the presence of these coexisting depressive symptoms.